# Faculty Career Scientist Position in ENT Focused AI Research

Source: https://realanalystjobs.com/job/faculty-career-scientist-position-in-ent-focused-ai-research-mayo-clinic-35b5ac95
Faculty Career Scientist Position in ENT Focused AI Research at Mayo Clinic, an on-site role based in Rochester, Minnesota, USA. Posted on 7 October 2026, read from Mayo Clinic's own careers page (Oracle HCM), which RealAnalystJobs re-checks daily and removes the role when it closes. Mayo Clinic has approved H-1B petitions on USCIS record (employer-wide, not a promise for this role).

Updated 15 November 2026.

## Key facts

- Company: [Mayo Clinic](https://realanalystjobs.com/companies/mayo-clinic)
- Location: Rochester, Minnesota, USA
- Work mode: On-site
- Posted: Oct 7, 2026
- Employment type: Full time
- Source: Mayo Clinic's careers page (Oracle HCM), re-checked daily

## Visa sponsorship

The posting does not say.

Mayo Clinic had H-1B petitions approved for 407 workers in fiscal year 2026 (USCIS). That is history, not a promise for this role. [See the record](https://realanalystjobs.com/companies/mayo-clinic#h1b-record)

## About this role

The Position
Mayo Clinic's Department of Otolaryngology-Head and Neck Surgery invites applications for a Career Scientist position in Rochester, Minnesota. This tenure-track-equivalent position is intended for a Ph.D. investigator from a broad range of computational, quantitative, engineering, and data-enabled disciplines to develop and lead an independent, externally funded research program focused on biomedical data science, computational biology, artificial intelligence, machine learning, or related quantitative disciplines applied to cancer and surgical care.

The successful candidate will join a highly collaborative, disease-focused translational research environment with direct integration across basic discovery, artificial intelligence, clinical investigation, population science, and high-volume surgical practice in head and neck oncology. The investigator's work should leverage advanced computational and analytical approaches to interrogate complex, multimodal datasets and generate clinically actionable insights that inform diagnosis, prognosis, treatment selection, therapeutic development, and surgical decision-making.

This recruitment is intentionally aligned with Mayo Clinic's Research Strategic Transformation priorities and Bold. Forward. vision. The successful candidate will be expected to help translate Mayo's unique clinical, molecular, imaging, pathology, biospecimen, outcomes, and real-world data resources into new knowledge, validated tools, and implementation-ready approaches that accelerate discovery and improve care for patients with head and neck diseases and cancer.

Mayo Clinic Platform and Data-Enabled Discovery
A distinguishing opportunity for this position is the ability to leverage Mayo Clinic Platform and related enterprise capabilities to advance discovery, validation, and implementation. Mayo Clinic Platform provides a growing ecosystem for real-world data, analytic tools, data science workspaces, and digital solution development that can support research, innovation, and care transformation. The candidate will be positioned to work with department, AI, informatics, quantitative sciences, and Platform partners to develop scalable, reusable approaches for data-enabled discovery.

The successful investigator may use Mayo Clinic Platform-enabled resources to support cohort discovery, multimodal phenotyping, model development and validation, real-world evidence generation, clinical trial feasibility, digital biomarker development, and translation of predictive models into clinical and operational workflows. This work should be grounded in responsible AI principles, including methodological rigor, transparency, data governance, bias mitigation, reproducibility, and close partnership with clinicians who understand the patient and surgical context.

Research Focus and Expectations
The successful candidate will be an emerging or established leader in biomedical data science with demonstrated expertise in one or more computational, quantitative, or data-enabled disciplines and a record of applying rigorous methods to complex biomedical, healthcare, or research datasets.. Depending on the candidate’s expertise and research program, relevant approaches may include: high-dimensional clinical, molecular, imaging, pathology, surgical, biospecimen-linked, and outcomes data to drive discovery in head and neck cancer and otolaryngology, with an emphasis on translation to clinically meaningful applications.

• Develop and apply artificial intelligence, machine learning, generative AI, computer vision, natural language processing, multimodal foundation models, multi-omic integration, digital pathology, radiomics, predictive modeling, and advanced statistical learning approaches.

• Create clinically meaningful tools and analytical frameworks that support diagnosis, prognosis, risk stratification, treatment response modeling, surgical planning, longitudinal surveillance, and clinical trial development.

• Advance AI-enabled surgical practice by using multimodal data from clinical encounters, imaging, pathology, operative workflows, surgical outcomes, biospecimens, genomics, and electronic health records to improve decision-making and patient outcomes.

• Partner closely with surgeon-scientists, clinician investigators, leaders, data scientists, biostatisticians, AI and informatics experts, and Mayo Clinic Platform teams to design rigorous translational studies and scalable analytic workflows.

• Develop and sustain a portfolio of extramural funding as principal investigator while contributing to large-scale team science, programmatic funding, industry collaborations, and cross-disciplinary initiatives.

• Produce high-impact publications, mentor trainees and junior faculty, contribute to national scientific committees and collaborative networks, and provide educational leadership within Mayo Clinic and the broader scientific community.

ENT and Head and Neck Oncology Environment
The Department of Otolaryngology-Head and Neck Surgery provides a differentiated environment for research that spans children and adults, acute and chronic disease, medical and surgical care, and multidisciplinary management of complex conditions. In head and neck cancer, departmental priorities include advanced diagnostics, early detection, prognostic tools, individualized treatment strategies, novel therapeutics, radiomics, biomarker discovery, genomic and molecular profiling, digital pathology, and improved connection with patients through digital health platforms.

The successful candidate will have opportunities to collaborate with teams investigating tumor microenvironments, methylation markers, circulating tumor DNA, machine learning applied to digitized histology, imaging modalities, surgical outcomes, and precision oncology. The candidate will also contribute to a broader departmental ambition to build data science, statistical programming, and AI-enabled research capacity that strengthens th

Description from Mayo Clinic's public careers feed, reproduced so you can read the role here. Apply on the company's own site; Real Analyst Jobs never submits anything for you.

## How to apply

Open [this role on Real Analyst Jobs](https://realanalystjobs.com/job/faculty-career-scientist-position-in-ent-focused-ai-research-mayo-clinic-35b5ac95) and use Apply now there to reach the employer's application. The listing is re-checked against Mayo Clinic's careers page daily and removed when it closes.

## Mayo Clinic

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## Sources and links

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